COL2A1 is a protein encoded by the COL2A1 gene which is approximately 141,7 kDa. COL2A1 is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling and focal adhesion. It is a fibrillar collagen that is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. COL2A1 isoform 2 is highly expressed in juvenile chondrocyte. Mutations in the COL2A1 gene may result in Spondyloepiphyseal dysplasia. STJ92387 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of COL2A1 protein.
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Număr Catalog 665-STJ92387CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune200 µlTipsingle
