STAT3 Luciferase Reporter-HEK293 C... BosterBio

STAT3 Luciferase Reporter-HEK293 Cell Line

The STAT3 Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter under the transcriptional control of the STAT3 responsive promoter, so that the cell line is designed to measure the transcriptional activity of STAT3. As a transcription factor, Signal Transducer and Activator of Transcription 3 (STAT3) is activated through phosphorylation at tyrosine 705 in response to various cytokines including IL-6, interferons, epidermal growth factor, hepatocyte growth factor and leukemia inhibitory factor. The phosphorylated STAT3 forms homodimers or heterodimers with STAT1, and the dimers translocate to nucleus in which DNA binding/promoter induction occurs. The STAT3 induction by IL-6 is shown in Figure 1.

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În stoc

Număr Catalog 519-RC1014

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.Tipsingle

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STAT3 Luciferase Reporter-HEK293 Cell Line

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