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DAB2 ELISA Kit (Human) : 96 Wells (OKEH01509)
Description of target: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL
794.4 EUR
Preț : 794.4 €
În stoc
Număr Catalog 247-OKEH01509
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune96 WellsTipsingle
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