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PCSK9 ELISA Kit (Human) (OKBB00903)
Description of target: Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A(EGF-A) domain of the low-density lipoprotein receptor(LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins(LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml
606 EUR
Preț : 606 €
În stoc
Număr Catalog 247-OKBB00903
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune96 WellsTipsingle
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