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Recombinant Mouse HIPK2 (N-GST tag)
 HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors. HIPK2 enhances expression of p53 target genes that resulting in growth arrest and the enhancement of UV-induced apoptosis that could be inhibited by antisense to HIPK2 . HIPK2 as a target for MDM2 mediated ubiquitin-dependent degradation that only occurred in growth-arresting conditions when MDM2 was efficiently induced by p53 . The knockdown of HIPK2 using small interfering RNA reduced p53 binding and activation of p53R2 that resulting in impaired UV-induced DNA repair.

370 EUR

370 EUR
În stoc
Număr Catalog 10021-Z600013
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune10 µgTipsingle
Produse asociate
Recombinant Mouse HIPK2 (N-GST tag)
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