Recombinant Human CK1 epsilon (N-G... ABM

Recombinant Human CK1 epsilon (N-GST tag)

CK1e is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes, including DNA replication and repair. CK1e is a regulator of Yes-associated protein (YAP) transcription coactivator which is a key regulator of organ size and a candidate human oncogene. CK1e is activated by CCK2R and this then phosphorylates PKD2 at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells . CKIe can phosphorylate topoisomerase (topo) IIalpha at serine-1106 and this regulates the enzyme activity and sensitivity to topo II-targeted drugs .

370 EUR

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Număr Catalog 10021-Z500086

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune10 µgTipsingle

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Recombinant Human CK1 epsilon (N-GST tag)

370 EUR

În stoc

Produse asociate

Recombinant Human CK1 epsilon (N-GST tag)

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Bloguri asociate

Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08