Recombinant Human CDK4/CyclinD3 (N... ABM

Recombinant Human CDK4/CyclinD3 (N-GST tag)

CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle. CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2). CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex . CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins. SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2 .

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În stoc

Număr Catalog 10021-Z500072

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune10 µgTipsingle

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Recombinant Human CDK4/CyclinD3 (N-GST tag)

Produse asociate

Recombinant Human CDK4/CyclinD3 (N-GST tag)

Recombinant Human CDK4/CyclinD3 (N-GST tag)

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Bloguri asociate

Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08