alpha-SMA is a protein encoded by the ACTA2 gene which is approximately 42 kDa. alpha-SMA is localised to the cytoplasm and cytoskeleton. It is involved in the PAK pathway, VEGF pathway, fMLP pathway and Sertoli-Sertoli cell junction dynamics. This protein falls under the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. It is an alpha actin that is found in skeletal muscle. alpha-SMA is expressed in the muscle, lung, nervous system, intestine and pancreas. Mutations in the ACTA2 gene may result in Moyamoya disease. STJ97382 was developed from clone 6A12 and was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. The antibody detects endogenous alpha-SMA protein.
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Număr Catalog 665-STJ97382CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune200 µlTipsingle
