Collagen III is a protein encoded by the COL3A1 gene which is approximately 138,5 kDa. Collagen III is secreted into the extracellular matrix. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling and the phospholipase-C pathway. It occurs in most soft connective tissues along with type I collagen. It is involved in regulation of cortical development and is the major ligand of ADGRG1 in the developing brain, binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13. Collagen III is expressed in the skin, pancreas, bone, liver and lung. Mutations in the COL3A1 gene may result in Ehlers-Danlos syndrome. STJ97025 was developed from clone Q76 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous Collagen III protein.
236.4EUR
236.4EUR
În stoc
Număr Catalog 665-STJ97025CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune200 µlTipsingle
