Cardiac troponin I, cTnI, is exclusively expressed in cardiac muscle tissue in a single isoform with molecular weight ~24 KD. cTnI forms complex with cardiac Troponin T (cTnT) and Troponin C (TnC) to regulate the formation of actomyosin filament and subsequent cardiac muscle contraction. During cardiac muscle tissue injury, cTnI is released into the blood of patient and indicative of cardiac cell death. cTnI has been widely used as a sensitive and specific diagnostic marker of acute myocardial infarction (AMI), post-surgery myocardium trauma, chemotherapy cardiotoxicity, and some other diseases linked to cardiac muscle injury. In recent years, high-sensitivity cTnI assay has been used to accurately diagnose AMI after the onset of acute chest pain.
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Număr Catalog 665-STJ130012CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune50 µlTipsingle
