Beta-TRCP Polyclonal Antibody Reddot Biotech

Beta-TRCP Polyclonal Antibody

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

Preț : 630 €

În stoc

Număr Catalog 866-RD82263A-200uL

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune200μLTipsingle

Produse asociate

Rabbit Anti Human Beta-TRCP Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence)

109-IRBAMLBTRCAP96200UL
each

530 €

BTRC (beta-Transducin Repeat Containing, BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, MGC4643, bTrCP, bTrCP1, betaTrCP) (HRP)

544-MBS6450600-5x01mL
5x0.1mL

3990 €

BTRC (beta-Transducin Repeat Containing, BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, MGC4643, bTrCP, bTrCP1, betaTrCP) (MaxLight 750)

544-MBS6450605-01mL
0.1mL

920 €

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