Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I , ‚à´, and , which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I (designated PIPK I ‚à´ in mouse) is expressed in brain tissue . PIPK I ‚à´, designated PIPK I a in mouse, is also called STM7. PIPK I has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.
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Număr Catalog 866-RD77841A-120uLCategorieAfaceri și industrie > Știință și laboratorFurnizorReddot BiotechGentaurDimensiune120μLTipsingle
