GDF-11, a member of the Transforming Growth Factor (TGF) Beta superfamily, controls anterior/posterior patterning of the axial skeleton, regulates organogenesis by controlling expression of Gdnf, contributes to the control of Hox gene expression, and induces phosphorylation of Smad2. In addition, GDF-11 mediates signaling of Nodal during left-right patterning and development of head structures and inhibits generation of new neurons by neuronal progenitors in the olfactory epithelium.
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Număr Catalog 992-R1510-15CategorieAfaceri și industrie > Știință și laboratorFurnizorHUABIOGentaurDimensiune100ulTipsingle