REST ELISA Kit (Rat) (OKWB00382) Aviva Systems Biology

REST ELISA Kit (Rat) (OKWB00382)

Description of target: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression ;Species reactivity: Rat;Application: ;Assay info: Assay Type: Quantitative Sandwich ELISA;Sensitivity: 10 pg/mL

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Număr Catalog 247-OKWB00382

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune96 WellsTipsingle

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REST ELISA Kit (Rat) (OKWB00382)

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