SPOP ELISA Kit (Human) (OKEI00190) Aviva Systems Biology

SPOP ELISA Kit (Human) (OKEI00190)

Description of target: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.469 ng/mL

Preț : 920.4 €

În stoc

Număr Catalog 247-OKEI00190

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune96 WellsTipsingle

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SPOP ELISA Kit (Human) (OKEI00190)

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