Description of target: Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.1 Publication
 <p>Manually curated information for which there is published experimental evidence.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.10"Biochemical analyses and molecular modeling explain the functional loss of 17beta-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development."_x005F_x005F_x000D_Engeli R.T., Rhouma B.B., Sager C.P., Tsachaki M., Birk J., Fakhfakh F., Keskes L., Belguith N., Odermatt A._x005F_x005F_x000D_J. Steroid Biochem. Mol. Biol. 155:147-154(2016) [PubMed] [Europe PMC] [Abstract]Cited for: VARIANT MPH ARG-133, CHARACTERIZATION OF VARIANT MPH ARG-133, FUNCTION, SUBCELLULAR LOCATION, MUTAGENESIS OF GLY-133. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 6.4 pg/mL
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Număr Catalog 247-OKCD00200CategorieAfaceri și industrie > Știință și laboratorFurnizorAviva Systems BiologyGentaurDimensiune96 WellsTipsingle
