KRAS inhibitor-16 (compound 3-11) is a potent KRAS G12C inhibitor with an IC50 of 0.457 µM. KRAS inhibitor-16 shows p-ERK inhibition activities with IC50s of 3.06, 11.1 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-16 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
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Număr Catalog 804-HY-146546CategorieAfaceri și industrie > Știință și laboratorFurnizorMedChemExpressGentaurDimensiuneGet quoteTipsingle