YS-370 (compound 44) is a potent, high selective, and orally active inhibitor of P-glycoprotein (P-gp). YS-370 stimulates the P-gp ATPase activity and has moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance (MDR) to paclitaxel and colchicine in SW620/AD300 and HEK293T-ABCB1 cells. YS-370 in combination with paclitaxel achieves much stronger antitumor activity[1].
7030.42RON
În stoc
Număr Catalog 804-HY-132866CategorieAfaceri și industrie > Știință și laboratorFurnizorMedChemExpressGentaurDimensiune10 mgTipsingle