N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3].
0.01EURAsk for quotation
0.01EURAsk for quotation
La cerere
Număr Catalog 804-HY-129099CategorieAfaceri și industrie > Știință și laboratorFurnizorMedChemExpressGentaurDimensiuneGet quoteTipsingle