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Biotin Anti-Mouse CD279/PD-1 Antibody
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
372.5 EUR
Preț : 372.5 €
În stoc
Număr Catalog 586-DL21639F-100ug
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune100μgTipsingle
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