ZAP-70(Phospho Tyr319) Polyclonal ... Jiaxing Korain Biotech Ltd (B...

ZAP-70(Phospho Tyr319) Polyclonal Antibody

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

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Număr Catalog 772-BT-AP15599-20ul

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune20ulTipsingle

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