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SIK1 Polyclonal Antibody
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-182 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,Contains 1 protein kinase domain.,Contains 1 UBA domain.,subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ.,subunit:Binds to and is activated by YWHAZ when phosphorylated on Thr-182.,
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Disponibil
Număr Catalog 772-BT-AP14226-100ul
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune100ulTipsingle
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