The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain| a disintegrin-like domain| as well as a EGF-like domain. Through its disintegrin-like domain| this protein specifically interacts with the integrin beta chain| beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner| suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Număr Catalog 772-BT-AP14126-100ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune100ulTipsingle
