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KDM3B Polyclonal Antibody
cofactor:Binds 1 Fe(2+) ion per subunit.,Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,Belongs to the JHDM2 histone demethylase family.,Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,
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Disponibil
Număr Catalog 772-BT-AP10662-100ul
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune100ulTipsingle
Produse asociate
KDM3B Polyclonal Antibody
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KDM3B Polyclonal Antibody
763-E-AB-92468-each
each
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