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Cyclin E1(Phospho-Thr62) Rabbit Polyclonal Antibody
The protein encoded by this gene belongs to the highly conserved cyclin family| whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2| whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors| which results in chromosome instability| and thus may contribute to tumorigenesis. This protein was found to associate with| and be involved in| the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus)| which participates in
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Disponibil
Număr Catalog 772-BT-AP08846-20ul
CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune20ulTipsingle
Produse asociate
Cyclin E1(Phospho-Thr62) Rabbit Polyclonal Antibody
772-BT-AP08846-100ul
100ul
Cere ofertă de preț
Cyclin E1(Phospho-Thr62) Rabbit Polyclonal Antibody
772-BT-AP08846-50ul
50ul
Cere ofertă de preț
Cyclin E1 (Phospho-Thr395) Polyclonal Conjugated Antibody
544-MBS9437161-01mLBiotin
0.1mL(Biotin)
480 €
Cyclin D1 (Phospho-Thr286) Polyclonal Conjugated Antibody
544-MBS9437417-01mLBiotin
0.1mL(Biotin)
480 €
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