The protein encoded by this gene is a member of the fibroblast growth factor receptor family| where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation. The genomic organization of this gene| compared to members 1-3| encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed| there is no evidence that the C-terminal half of the IgII
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Număr Catalog 772-BT-AP06216-100ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune100ulTipsingle
