This gene encodes a cytokine that belongs to the interferon family of signaling proteins| which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons| which are important for defense against viral infections. In addition| type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen| type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
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Număr Catalog 772-BT-AP02022-50ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune50ulTipsingle