The PARP11 Chemiluminescent Assay Kit is designed to measure the activity of PARP11 (poly- (ADP-ribose) polymerase 11) for screening and profiling applications. The PARP11 assay kit comes in a convenient 96-well format, with enough recombinant purified PARP11 enzyme (amino acids 8-338), reaction substrate, and PARP assay buffer for 100 enzyme reactions.Figure 1. PARP11 Chemiluminescent Assay Kit schematic.Histone proteins are coated on a 96-well plate. Next, a biotinylated NAD+mix (termed PARP Substrate Mixture) is incubated with the PARP11 enzyme in an optimized assay buffer. The plate is then treated with streptavidin-HRP followed by addition of the ELISA ECL substrate to produce chemiluminescence that can be measured using a chemiluminescence reader. The chemiluminescence signal is proportional to the PARP11 activity.Need us to run inhibitor screens or profile your compounds against PARP11? Check out ourPARP/PARPTrap™ Screening ServicesorDNA Replication and Repair Screening Services.This product has beencited 2 times.
1160EUR
Preț : 1160 €
În stoc
Număr Catalog 421-80561CategorieAfaceri și industrie > Știință și laboratorFurnizorBPS BioscienceGentaurDimensiune96 rxns.Tipsingle