The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).
923.69RON
În stoc
Număr Catalog 223-8005-002mgCategorieAfaceri și industrie > Știință și laboratorFurnizorProSciGentaurDimensiune0.02 mgTipsingle