Spike (XBB.1.16, Omicron Variant) ... BPS Bioscience

Spike (XBB.1.16, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (eGFP Reporter)

The Spike (XBB.1.16 Omicron Variant) (SARS-CoV-2) Pseudotyped Lentiviruses are replication incompetent, HIV-based lentiviral particles. They were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1 containing all the Omicron XBB.1.16 mutations; see below for details) as the envelope glycoprotein instead of the commonly used VSV-G. These pseudovirions contain eGFP driven by a CMV promoter (Figure 1), allowing the spike-mediated cell entry to be measured by the eGFP fluorescence signal. The Spike (XBB.1.16, Omicron Variant) (SARS-CoV-2) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 XBB.1.16.The Spike Omicron XBB.1.16 pseudoviruses have been validated for use with ACE2-HEK293 target cells (which overexpress ACE2; BPS Bioscience #79951) .Figure 1. Schematic of the lenti-vector used to generate the eGFP Reporter in the Spike (XBB.1.16, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus.

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Număr Catalog 421-78785-1

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune100 µLTipsingle

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Spike (XBB.1.16, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (eGFP Reporter)

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Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08