The Spike Trimer (S1+S2) (B.1.1.529 BA.1, Omicron Variant) (SARS-CoV-2) : ACE2 Inhibitor Screening Chemiluminescence Assay Kit is designed for screening and profiling inhibitors or neutralizing antibodies of the interaction between the SARS-CoV-2 Omicron variant Spike Trimer and human ACE2 (angiotensin-converting enzyme 2) . This kit comes in a convenient 96-well format, with Biotinylated-ACE2 (amino acids 18-740), purified Spike Trimer protein (B.1.1.529 BA.1, Omicron Variant) (amino acids 16-1213), Streptavidin-HRP, and assay buffers for 100 reactions. The SARS-CoV-2 Spike Trimer, included in the kit, provides a biologically relevant model for the investigation of SARS-CoV-2/ACE2 interaction.Figure 1. Assay Kit schematic.First, SARS-CoV-2 Spike Trimer (S1+S2) (B.1.1.529 BA.1, Omicron Variant) is coated on a 96-well plate overnight. After washing and blocking, the protein is pre-incubated with an inhibitor or neutralizing antibody. Upon subsequent incubation with Biotin-ACE2, the plate is treated with Streptavidin-HRP.After a final wash, ELISA ECL substrate is added to produce chemiluminescence that can be measured using a chemiluminescence reader.The chemiluminescence signal is proportional to the efficacy of the binding of Spike Trimer (S1+S2) (B.1.1.529 BA.1, Omicron Variant) to ACE2.Interested in having us perform the screening and profiling of inhibitors or blocking antibodies? Visit ourCoronavirus Servicepage.
995EUR
Preț : 995 €
În stoc
Număr Catalog 421-78369CategorieAfaceri și industrie > Știință și laboratorFurnizorBPS BioscienceGentaurDimensiune96 rxns.Tipsingle
