Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
523.7EUR
Preț : 523.7 €
În stoc
Număr Catalog 223-7809-01mgCategorieAfaceri și industrie > Știință și laboratorFurnizorProSciGentaurDimensiune0.1 mgTipsingle
