The JMJD2C Homogeneous Assay Kit is designed to measure JMJD2C activity for screening and profiling applications. JMJD2C is a JumonjiC (JmjC) domain containing histone lysine demethylase that exhibits demethylation activity toward H3-K9Me3and H3-K36Me3. The JMJD2C Homogeneous Assay Kit comes in a convenient AlphaLISA®format (Scheme 1), with biotinylated histone H3 peptide substrate, primary antibody, demethylase assay buffer, and purified JMJD2C for 96 or 384 enzyme reactions. The key to the JMJD2C Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing JMJD2C enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.Need us to run inhibitor screens or profile your compounds against JMJD2C (KDM4C) ? Check out ourDemethylase Screening Services.
1875EUR
Preț : 1875 €
În stoc
Număr Catalog 421-50415-2CategorieAfaceri și industrie > Știință și laboratorFurnizorBPS BioscienceGentaurDimensiune384 rxns.Tipsingle
