Ai nevoie de ajutor? [email protected]

product
LDH (Plasmodium falciparum) Recombinant Protein
Malaria is one of the most widespread infectious diseases affecting some 500 million people with an enormous cost in human suffering and economic hardship. Effective treatment of the disease is increasingly compromised by rising resistance of malaria parasites to currently available anti-malarials. The parasites are homolactate fermenters and rely on glycolysis for energy generation since the parasites appear to lack a functional citric acid cycle. The NAD+ consumed during glycolysis is reduced to NADH by lactate which, in turn, is oxidized to pyruvate. This reaction is catalyzed by lactate dehydrogenase (LDH). It has been demonstrated that inhibitors of this enzyme have parasiticidal activity. Since LDH from the malaria parasite Plasmodium falciparum (PfLDH) has notable structural and kinetic differences from human LDHs, the enzyme appears to be an attractive target for novel anti-malarial therapeutics. The parasite, P. falciparum, is the most lethal of malarial plasmodia being responsible for the cerebral form of the disease; consequently it has been the major focus of initial biochemical and genomic investigation. On the other hand, the parasite P. vivax is of great importance as it is the most widespread and common of the malarial plasmodia and, therefore, is responsible for the greatest burden of disease.

Cerere de ofertă

La cerere
Număr Catalog 209-400-003
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune25 µgTipsingle
Produse asociate
Recombinant Plasmodium Falciparum LDH Protein (aa 1-316)
708-VAng-Wyb6520-25g
25 µg
11063.81 RON
Plasmodium falciparum LDH Protein
827-REC31737-100
0.1
3022.57 RON
Recombinant Plasmodium Falciparum HRP2 Protein
708-VAng-Wyb6329-500g
500 µg
23665.15 RON
Recombinant Plasmodium falciparum Myb1 protein (myb1)
544-MBS1432431-002mgBaculovirus
0.02mg(Baculovirus)
5756.8 RON
Bloguri asociate
Ce este microbiologia? – istorie și domenii
Postat de

Întreaga noastră lume este alcătuită din micr...

Accidentul vascular cerebral – cele mai importante informații
Postat de

Pe măsură ce înaintăm în vârstă, riscul de a ...

Pepsina – ce este și unde se găsește?
Postat de

În magazinele cu produse naturiste și pe dive...

Te ajutăm să găsești cele mai bune produse pentru cercetarea ta și îți răspundem la întrebări prin chat, email sau telefon. Nu ezita să ne contactezi