1,10-Phenanthroline, Monohydrate BPS Bioscience

1,10-Phenanthroline, Monohydrate

1,10-phenanthroline (o-phenanthroline) is a chelator with high affinity for divalent metal ions. When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn<sup>2+</sup> ion. As such, o-phenanthroline is widely used when preparing cell lysates for enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.

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Număr Catalog 421-27713

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune0.5 mlTipsingle

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1,10-Phenanthroline, Monohydrate

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Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08