Ub is a protein encoded by the UBA52 gene which is approximately 14,7 kDa. Ub is localised to the cytoplasm and nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, RET signalling, activated TLR4 signalling, viral mRNA translation and the HIV life cycle. Ubiquitin exists either covalently attached to another protein, or free. When attached to a target protein, it has different functions depending on the Lys residue of the ubiquitin that is linked to. These functions including DNA repair and cell cycle regulation. Ub is expressed in the blood, nervous system, adrenal gland, muscle and liver. Mutations in the UBA52 gene may result in stomatitis. STJ96863 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Ub protein.
236.4EUR
236.4EUR
În stoc
Număr Catalog 665-STJ96863CategorieAfaceri și industrie > Știință și laboratorFurnizorSt John's LaboratoryGentaurDimensiune200 µlTipsingle
