CDKN1A ELISA Kit (Mouse) (OKCA02364) Aviva Systems Biology

CDKN1A ELISA Kit (Mouse) (OKCA02364)

Description of target: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex . Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: 1.95 pg/mL

Preț : 1015.2 €

În stoc

Număr Catalog 247-OKCA02364

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune96 WellsTipsingle

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CDKN1A ELISA Kit (Mouse) (OKCA02364)

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