Anti-BubR1 Antibody HUABIO

Anti-BubR1 Antibody

Human cells contain two related protein kinases, BUB1 and BUBR1, that appear to have evolved from a single ancestral BUB1 gene. Both kinases are concentrated near the surface of the kinetochore where they monitor kinetochore-microtubule interactions. BUB1 and BUBR1 bind to kinetochores and are postulated to be components of the mitotic checkpoint, which monitors kinetochore activities to determine if chromosomes have achieved alignment at the spindle equator. BUBR1 is essential for normal mitotic progression as it prevents cells from prematurely entering anaphase. BUB3 is a conserved component of the mitotic spindle assembly complex and is also involved with the essential spindle checkpoint pathway that operates during early embryogenesis.

189 EUR

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Număr Catalog 992-ER1802-76

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune100ulTipsingle

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Anti-BubR1 Antibody

189 EUR

În stoc

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Anti-BubR1 antibody

Anti-BubR1 antibody

Anti-BubR1 antibody

Anti-BubR1/BUB1B Antibody (Monoclonal, 8B3)

Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI11G2 (formerly 11G2)

Anti-Bub3 antibody

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Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08