The protein encoded by this gene is a member of the TNF-receptor superfamily| and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L)| and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD| a death domain containing adaptor protein| is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
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Număr Catalog 772-BT-AP09336-100ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune100ulTipsingle