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MGMT Polyclonal Antibody
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. Methylated-DNA--protein-cysteine methyltransferase encoded by MGMT is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. Methylated-DNA--protein-cysteine methyltransferase catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma.
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Disponibil
Număr Catalog 772-BT-AP05395-100ul
CategorieAfaceri și industrie > Știință și laborator
FurnizorGentaurDimensiune100ulTipsingle
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