This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance| growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse| and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders| and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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La cerere
Număr Catalog 772-BT-AP00477-100ulCategorieAfaceri și industrie > Știință și laboratorFurnizorJiaxing Korain Biotech Ltd (BT Labs)GentaurDimensiune100ulTipsingle
