HMGB1 Recombinant Protein ProSci

HMGB1 Recombinant Protein

HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as a ligand for RAGE, TLR-2 and TLR-4 expressed on surrounding cells. As a result, HMGB1 activates Rac, CDC42 and NF-kappaB inducing localized innate immunity of damaged tissue, tissue regeneration by recruitment of stem cells and hemostasis by induction of tissue factor expression. HMGB1 is also causative agent of various diseases as it causes localized inflammation such as arteriosclerosis, chronic rheumatoid arthritis and nephritis.

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Număr Catalog 223-90-457

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune25 ugTipsingle

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HMGB1 Recombinant Protein

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HMGB1 Recombinant Protein

HMGB1 Recombinant Protein

HMGB1 Recombinant Protein

Recombinant Human HMGB1 Protein

Recombinant Human HMGB1 Protein

OPCD03917-50UG - HMGB1 Recombinant Protein

Bloguri asociate

Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08