BMI-1 Antibody ProSci

BMI-1 Antibody

BMI-1 Antibody: The transcriptional repressor BMI-1 was first identified as a proto-oncogene frequently activated by Moloney murine leukemia proviral insertions in mice and cooperating with c-myc in the generation of mouse lymphomas. BMI-1 is involved in segment specification, cell growth and maintenance, transcriptional regulation, and chromatin modification. A major target of BMI-1 is the ink4a locus which encodes tumor suppressor proteins p16 and p19Arf, which are important in tumor progression and thought to be critical in cell proliferation and senescence. Recent studies have also shown that BMI-1 is required for the maintenance of adult normal and leukemic stem cells, suggesting that BMI-1 could an attractive therapeutic target for stem cell proliferation and renewal as well as for anti-cancer strategies.

523.7 EUR

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Număr Catalog 223-3755-01mg

CategorieAfaceri și industrie > Știință și laboratorFurnizorGentaurDimensiune0.1 mgTipsingle

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BMI-1 Antibody

523.7 EUR

În stoc

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BMI-1 Antibody

BMI-1 Antibody

BMI-1 Antibody

AbFlex BMI-1 antibody (rAb)

Polycomb Complex Protein BMI-1 (BMI1) Antibody

Polycomb Complex Protein BMI-1 (BMI1) Antibody

Bloguri asociate

Contact

Belgia (BE): +32 2 265 09 20

Franța (FR): +33 1 88 38 07 37

Regatul Unit (UK): +44 20 33 938 531

Polonia (PL): +48 58 710 33 44

Germania (DE): +49 241 936 88 188

Statele Unite (US): +1 408 780 09 08