Principiu

Testul de detectare a antigenului COVID-19 este un test de imunotest pentru detectarea rapidă și calitativă a infecției cu SARS-CoV-2 de la probe tamponate. Anticorpii monoclonali anti-SARS-CoV-2 sunt acoperiți pe regiunea liniei de testare. Antigenii SARS-CoV-2, dacă sunt prezenți în eșantioane, vor interacționa cu anticorpii monoclonali antiSARS-CoV-2 conjugați cu conjugatul de aur care fac complexul antigen-anticorpi conjugat. Acest complex migrează pe membrană prin acțiune capilară, unde va fi captat de anticorpul monoclonal anti-SARS-CoV-2 acoperit pe linia de testare. O linie de test colorată ar fi vizibilă în fereastra de rezultat dacă antigenii SARS-CoV-2 sunt prezenți în specimen. Intensitatea liniei de testare colorate va varia în funcție de cantitatea de antigen SARS-CoV-2 prezent în specimen.

Îndrumări pentru utilizarea COVID-19 Ag Respi-Strip (CorisBioConcept)

ICMR a validat recent 13 truse de testare antigen COVID-19. Dintre acestea, 3 kituri au fost aprobate pentru utilizare până
acum:
1. STANDARD Q COVID-19 Ag de SD Biosensor
2. COVID-19 Antigen Lateral Test Device of Lab Care Diagnostics Ltd.
3. * COVID-19 Ag Respi-Strip ( CorisBioConcept)
* COVID-19 Ag Respi-Strip (Coris BioConcept) implică o metodologie diferită de testare în comparație cu
celelalte două truse de testare a antigenului aprobate de ICMR până acum. Acest test nu poate fi efectuat la pat și
necesită o configurare BSL-2 pentru a rula testul.

Scurtă metodologie de utilizare a COVID-19 Ag Respi-Strip (CorisBioConcept):

1. Tamponul nazofaringian și / sau orofaringian va fi colectat de la pacientul suspect COVID-19 în
mediu de transport viral (VTM).
2. Tamponul colectat în VTM va fi adus la laborator în condiții corespunzătoare ale lanțului de frig.
3. Odată ce proba este adusă la laborator, va trebui manipulată într-un dulap de nivel BSL-2 pentru
alicotare, punerea în tampon de liză și încărcarea benzii de testare.
 Etapele 1 și 2 vor fi efectuate conform practicii standard urmate pentru colectarea și transportul
probelor pentru testul COVID-19 RT-PCR.
 Pasul 3 va trebui efectuat conform instrucțiunilor producătorilor furnizate împreună cu kitul de testare.

Biocredit Covid-19 Ag Detection Kit
G61RHA20	RapiGEN	20 test cards (pkg)	EUR 95

COVID-19 IgG/IgM Rapid Test Kit
UNCOV-20	UnScience	20T/kit	EUR 155
Description: COVID-19 IgG/IgM Rapid Test (Serum/Plasma/Whole Blood) is a qualitative membrane-based immunoassay for the detection of COVID-19 antibodies in serum, plasma, or whole blood. This test consists of two test lines, an IgG line and an IgM line, which is pre-coated with two mouse anti-human monoclonal antibodies separately. During testing, the sample reacts with COVID-19 antigen-coated on conjugated pad. As the complex continues to travel up the strip, the anti-COVID-19 IgM antibodies are bound on the IgM line, and the anti-COVID-19 IgG antibodies are bound on the IgG line. The control(C)line appears when sample has flowed through the strip. The presence of anti-COVID-19 IgM and/or IgG will be indicated by a visible test line in the IgM and IgG region. To serve as a procedural control, the control line should always appear if the test procedure is performed properly and the reagents are working as intended.

Panbio™ COVID-19 IgG/IgM Rapid Test
ICO-T402	Abbott	25 Tests/Kit	EUR 220

Panbio™ COVID-19 Ag Rapid Test Device
41FK10	Abbott	25 Tests/Kit	EUR 99

Panbio™ COVID-19 Ag Rapid Test Device (Nasal)
41FK11	Abbott	25 Tests/Kit	EUR 99
Description: The Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 is a β -coronavirus, which is an enveloped non-segmented positive-sense RNA virus 2. It is spread by human-to-human transmission via droplets or direct contact, and infection has been estimated to have a mean incubation period of 6.4 days and a basic reproduction number of 2.24-3.58. Among patients with pneumonia caused by SARS-CoV-2, fever was the most common symptom, followed by cough3. The main IVD assays used for COVID-19 employ real-time reverse transcriptase-polymerase chain reaction (RT-PCR) that takes a few hours 4. The availability of a cost-effective, rapid point- of-care diagnostic test is critical to enable healthcare professionals to aid in the diagnosis of patients and prevent further spread of the virus5. Antigen tests will play a critical role in the fight against COVID-19

TESTO (Testosterone) ELISA test
19	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of O (osterone)

COVID-19 IgG & IgM antibody
GEN-50001-50tests	Ring Bio	50 tests	EUR 324
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

PCRAgH5 AIV Detection Test Kit
PD55-02	Bionote	1 kit	EUR 902.47
Description: Please check the datasheet of PCRAgH5 AIV Detection Test Kit before using the test.

NATtrol Zika Virus Stock (Qualitative) (1 mL)
TEST	Zeptometrix	1 mL	EUR 1106.64
Description: Please contact Gentaur in order to receive the datasheet of the product.

Novel Coronavirus COVID-19 (2019-nCoV) Real Time Multiplex RT-PCR Kit (Detection for 3 Genes )
RR-0479-02	Liferiver	25 tests/kit	EUR 1347
Description: Novel Coronavirus (2019-nCoV) Real Time Multiplex RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems. It detects N gene, E gene and RdRp gene of 2019-nCoV. RR-0479-02 has been also approverd by CFDA for emergency use and is WHO standard.

CA125 (Cancer antigen) ELISA test
11	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of CA125 (Cancer antigen)

CA153 (Cancer antigen) ELISA test
12	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of CA153 (Cancer antigen)

CA199 (Cancer antigen) ELISA test
13	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of CA199 (Cancer antigen)

CEA (Cancer antigen) ELISA test
9	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

Purified recombinant COVID-19 (isolate Wuhan-Hu-1) NP protein
nCoVNP-126V	Creative BioMart	100ug	EUR 792
Description: Purified recombinant COVID-19(isolate Wuhan-Hu-1) NP protein was expressed in HEK293 cells.

Recombinant COVID-19 (isolate Wuhan-Hu-1) S(ΔTM) protein
nCoVS-125V	Creative BioMart	100ug	EUR 792
Description: Purified recombinant COVID-19(isolate Wuhan-Hu-1) S(ΔTM) protein was expressed in HEK293 cells.

PSA (Prostate-specific antigen) ELISA test
8	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit
RR-0478-02	Liferiver	25 tests/kit	EUR 991
Description: Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems.

HBsAg hepatitis B surface antigen ELISA test
77	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of HBsAg hepatitis B surface antigen

HBeAg hepatitis B E antigen ELISA test
79	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of HBeAg hepatitis B E antigen

HEV-Ag hepatitis E antigen ELISA test
94	Biobase	96T/Box	Ask for price
Description: ELISA based test for quantitative detection of HEV-Ag hepatitis E antigen

SARS-CoV-2 Rapid Antigen Test Nasal
9901-NCOV-03G	Roche Diagnostics	25 Tests/Kit	EUR 94
Description: The SARS-CoV-2 Rapid Antigen Test is a lateral fl ow rapid chromatographic immunoassay for the qualitative detection of nucleocapsid antigen to SARS-CoV-2 present in human nasal samples. This test is intended for use as an aid in detection of SARS-CoV-2 infection in individuals suspected of COVID-19 with clinical symptoms onset within 5 days. Results are for the identification of SARS-CoV-2 nucleocapsid antigen. Antigen is generally detectable in human nasal swab samples during the acute phase of infection. Positive results indicate the presence of viral antigens, but clinical correlation with patient history and other diagnostic information is necessary to determine infection status. Positive results do not rule out bacterial infection or co- infection with other viruses. The agent detected may not be the definite cause of disease. Negative results should be treated as presumptive, and do not rule out SARS-CoV-2 infection and should not be used as the sole basis for treatment or patient management decisions, including infection control decisions. Negative results should be considered in the context of a patient’s recent exposures, history and the presence of clinical signs and symptoms consistent with COVID-19, and confirmed with a molecular assay, if necessary, for patient management. The SARS-CoV-2 Rapid Antigen Test is intended for use in laboratory or POC settings by healthcare professionals, or self-collection under the supervision of a healthcare worke

SARS-CoV-2 Antigen Rapid Test Kit
CoV2Ag-1	UnScience	1T	EUR 8
Description: This kit adopts the sandwich method and the technical principle of colloidal gold immunochromatography to qualitative determine the SARS-CoV-2 antigen. During the test, the sample is dropped into the sample well, and chromatography is performed under the capillary effect. The SARS-CoV-2 antigen in the sample combined with the colloidal goldlabeled SARS-CoV-2 monoclonal antibody I, and then spread to the test area. It is captured by another coated antibody (SARS-CoV-2 monoclonal antibody II), to form a complex and gather in the test area (T line). The quality control area is coated with the goat antimouse antibody, and the colloidal gold-labeled antibody is captured to form a complex and aggregate in the quality control area (C line). If the C line does not show color, it indicates that the result is invalid, and this sample needs to be tested again.

SARS-CoV-2 Antigen Rapid Test Kit
CoV2Ag-25	UnScience	25T/kit	EUR 35
Description: This product is used for in vitro qualitative detection of SARS-CoV-2 antigen in human oropharyngeal swabs, nasal swabs and nasopharyngeal swabs. It is helpful as an aid in the screening of early mild, asymptomatic, or acute patients for identification of SARS-CoV-2 infection.

Cancer Antigen 19-9 Antigen (Liver Carcinoma)
VAng-Cr3873-10kU	Creative Biolabs	10 kU	EUR 394
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma. The purity is detected by gel filtration and ion-exchange chromatography. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Cannabinoid (THC)-BSA Antigen (AG310 (detection))
VAng-Cr3665-1mg	Creative Biolabs	1 mg	EUR 738
Description: Cannabinoid (THC)-BSA Antigen, matched pairs: AG310 (detection); Used for Lateral Flow.

Rat IL-19(Interleukin 19) ELISA Kit
ER1589	FN Test	96T	EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 9.8pg/ml

Human IL-19(Interleukin 19) ELISA Kit
EH3268	FN Test	96T	EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml