Anticorpii anti-NHS sunt oferiți de un număr de furnizori. Această genă țintă codifică proteina „regulator de remodelare a actinei NHS” la om și poate fi cunoscută și sub denumirea de CTRCT40, CXN, SCML1, proteina sindromului Nance-Horan și sindromul Nance-Horan (cataracta congenitală și anomalii dentare). Structural, proteina este raportată a avea o masă de 179,1 kilodaltoni. Pe baza denumirii genei, pot fi găsiți, de asemenea, ortologi canini, porcini, maimuțe, șoareci și șobolani.
Descrierea proteinei de legare a ADN-ului H-NS (hns)
Numele produsului | Proteina de legare a ADN-ului H-NS (hns) |
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ID-ul Uniprot | P0ACF9 |
Uniprot link | https://www.uniprot.org/uniprot/P0ACF9 |
Sistem de expresie | Expresie procariotică |
Secvenţă | MGSHHHHHHSGLEVLFQGPMSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVNERREEESAAAAEVEERTRKLQQY REMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDENGETKTWTGQGRTPAVIKKDDFL |
Greutate moleculară | 17,63kDa |
Puritate estimată | 40% prin SDS-PAGE |
Tampon | 20 mM Tris HCI, pH 8,0, 2 mM MgCl2 și 20 mM NaCI |
Conditii de livrare | Gheață albastră (+ 4 °) |
Termen de livrare în zile lucrătoare | Europa: 5-7 zile lucrătoare SUA și Canada: 7-10 zile lucrătoare Restul lumii: 5-12 zile lucrătoare |
Starea de depozitare | 4 ° C pe termen scurt (1 săptămână), -20 ° C sau -80 ° C pe termen lung (evita ciclurile de îngheț / decongelare; adăugarea de 20-40% glicerol îmbunătățește crioprotecția) |
Marca | ProteoGenix |
Specii gazdă | Escherichia coli (E.coli) |
Tipul fragmentului | Met12-Gln156 |
Aliasuri / Sinonime | Proteina de legare a ADN-ului H-NS, proteina asemănătoare histonei HLP-II, Proteina B1, Proteina H1 |
Referinţă | PX-P4380 |
Notă | Doar pentru cercetare |
Profiluri de legare diferențiale ale StpA în celule mutante de tip sălbatic și hns : o analiză comparativă a partenerilor cooperativi prin analiza imunoprecipitării-microarray a cromatinei
ABSTRACT
Am efectuat analize de imunoprecipitare a cromatinei-microarray pentru a investiga diferențele în funcție între StpA și H-NS în celulele Escherichia coli . Regiunile de legare StpA se suprapun în esență cu cele ale H-NS în celulele de tip sălbatic, în timp ce acestea sunt reduse la o treime în mutantul hns .
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